Juhani JÄNNE : rechercher sur Z-Library

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1

Transgenic Animals as Bioproducers of Therapeutic Proteins

Jänne, Juhani, Hyttinen, Juha-Matti, Peura, Teija, Tolvanen, Minna, Alhonen, Leena, Halmekytö, Maria

Journal:

Annals of Medicine

Année:

1992

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1992

2

Low-order controller design using remotely measured time delayed signals for stabilisation of equivalent power grid

Purwar, Shubhi, Nikkilä, Antti-Juhani, Turunen, Jukka, Seppänen, Janne M., Kishor, Nand, Haarla, Liisa C.

Journal:

IET Generation Transmission & Distribution

Année:

2015

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2015

3

Towards the EU emissions targets of 2050: optimal energy renovation measures of Finnish apartment buildings

Hirvonen, Janne, Jokisalo, Juha, Heljo, Juhani, Kosonen, Risto

Journal:

International Journal of Sustainable Energy

Année:

2018

Langue:

english

Fichier:

PDF, 3.53 MB

english, 2018

4

Towards the EU Emission Targets of 2050: Cost-Effective Emission Reduction in Finnish Detached Houses

Hirvonen, Janne, Jokisalo, Juha, Heljo, Juhani, Kosonen, Risto

Journal:

Année:

2019

Fichier:

PDF, 2.60 MB

2019

5

Hypermethylation of calcitonin gene regulatory sequences in human breast cancer as revealed by genomic sequencing

Mika Hakkarainen, Jarmo Wahlfors, Sanna Myöhänen, Mikko O. Hiltunen, Matti Eskelinen, Risto Johansson, Juhani Jänne

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 521 KB

english, 1996

6

Hypermethylation of the APC (adenomatous Polyposis Coli) gene promoter region in human colorectal carcinoma

Mikko O. Hiltunen, Leena Alhonen, Jari Koistinaho, Sanna Myöhänen, Matti Pääkkönen, Sinikka Marin, Veli-Matti Kosma, Juhani Jänne

Journal:

International Journal of Cancer

Année:

1997

Langue:

english

Fichier:

PDF, 206 KB

english, 1997

7

Evaluation of herpes simplex thymidine kinase mediated gene therapy in experimental pancreatic cancer

Kimmo Mäkinen, Sami Loimas, Jarmo Wahlfors, Esko Alhava, Juhani Jänne

Journal:

The Journal of Gene Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 178 KB

english, 2000

8

Application of dynamic pressure probe technique to characterize a circulating fluidized bed

Janne H. Pärssinen, Pasi Hagelberg, Isto Eilos, Juhani Aittamaa

Journal:

The Canadian Journal of Chemical Engineering

Année:

1999

Langue:

english

Fichier:

PDF, 661 KB

english, 1999

9

Neuropsychiatric symptoms and Quality of Life in patients with very mild and mild Alzheimer's disease

Kristiina Karttunen, Pertti Karppi, Asta Hiltunen, Matti Vanhanen, Tarja Välimäki, Janne Martikainen, Hannu Valtonen, Juhani Sivenius, Hilkka Soininen, Sirpa Hartikainen, Jaana Suhonen, Tuula Pirttilä

Journal:

International Journal of Geriatric Psychiatry

Année:

2011

Langue:

english

Fichier:

PDF, 156 KB

english, 2011

10

Polyamine biosynthesis inhibition enhances HSV-1 thymidine kinase/ganciclovir-mediated cytotoxicity in tumor cells

Tiina Pasanen, Anne Karppinen, Leena Alhonen, Juhani Jänne, Jarmo Wahlfors

Journal:

International Journal of Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 158 KB

english, 2003

11

In vivo enhancement of herpes simplex virus thymidine kinase/ganciclovir cancer gene therapy with polyamine biosynthesis inhibition

Tiina Wahlfors, Tanja Hakkarainen, Juhani Jänne, Leena Alhonen, Jarmo Wahlfors

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 150 KB

english, 2006

12

Life-long over-expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration

Leena Alhonen, Maria Halmekytö, Veli-Matti Kosma, Jarmo Wahlfors, Risto Kauppinen, Juhani Jänne

Journal:

International Journal of Cancer

Année:

1995

Langue:

english

Fichier:

PDF, 374 KB

english, 1995

13

Transgenic bioreactors

Juhani Jänne, Juha-Matti Hyttinen, Teija Peura, Minna Tolvanen, Leena Alhonen, Rlitta Sinervirta, Maria Halmekytö

Journal:

International Journal of Biochemistry

Année:

1994

Langue:

english

Fichier:

PDF, 1.21 MB

english, 1994

14

Analysis of underivatized polyamines by reversed phase liquid chromatography with electrospray tandem mass spectrometry

Merja R. Häkkinen, Tuomo A. Keinänen, Jouko Vepsäläinen, Alex R. Khomutov, Leena Alhonen, Juhani Jänne, Seppo Auriola

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2007

Langue:

english

Fichier:

PDF, 686 KB

english, 2007

15

Synthesis of novel optical isomers of α-methylpolyamines

Nikolay A. Grigorenko, Alex R. Khomutov, Tuomo A. Keinänen, Aki Järvinen, Leena Alhonen, Juhani Jänne, Jouko Vepsäläinen

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 206 KB

english, 2007

16

Synthesis of novel deuterium labelled derivatives of N-alkylated polyamines

Merja R. Häkkinen, Tuomo A. Keinänen, Alex R. Khomutov, Seppo Auriola, Janne Weisell, Leena Alhonen, Juhani Jänne, Jouko Vepsäläinen

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 626 KB

english, 2009

17

Antitumor activity and metal complexes of the first transition series. Trans-bis(salicylaldoximato)copper(II) and related copper(II) complexes, a novel group of potential antitumor agents

Paavo Lumme, Hannu Elo, Juhani Jänne

Journal:

Inorganica Chimica Acta

Année:

1984

Langue:

english

Fichier:

PDF, 873 KB

english, 1984

18

CD80 antigen expression as a predictor of ex vivo chemosensitivity in chronic lymphocytic leukemia

Ilkka Kivekäs, Janne Hulkkonen, Mikko Hurme, Leena Vilpo, Juhani Vilpo

Journal:

Leukemia Research

Année:

2002

Langue:

english

Fichier:

PDF, 77 KB

english, 2002

19

Diminished production of interleukin-6 in chronic lymphocytic leukaemia (B-CLL) cells from patients at advanced stages of disease

Janne Hulkkonen, Juhani Vilpo, Leena Vilpo, Mikko Hurme, for the Tampere CLL Group

Journal:

British Journal of Haematology

Année:

1998

Langue:

english

Fichier:

PDF, 663 KB

english, 1998

20

Response to vaccination against different types of antigens in patients with chronic lymphocytic leukaemia

Marjatta Sinisalo, Janne Aittoniemi, Petri Oivanen, Helena Käyhty, Rose-Marie Ölander, Juhani Vilpo

Journal:

British Journal of Haematology

Année:

2001

Langue:

english

Fichier:

PDF, 118 KB

english, 2001

21

Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats

Jouko A. Lukkarinen, Risto A. Kauppinen, Olli H. J. Gröhn, Joni M. E. Oja, Riitta Sinervirta, Aki Järvinen, Leena I. Alhonen, Juhani Jänne

Journal:

European Journal of Neuroscience

Année:

1998

Langue:

english

Fichier:

PDF, 567 KB

english, 1998

22

Overexpression of spermidine/spermine N1-acetyltransferase in transgenic mice protects the animals from kainate-induced toxicity

Kyllikki Kaasinen, Jari Koistinaho, Leena Alhonen, Juhani Jänne

Journal:

European Journal of Neuroscience

Année:

2000

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2000

23

Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase

Pietilä, Marko, Parkkinen, Jyrki J, Alhonen, Leena, Jänne, Juhani

Journal:

The Journal of Investigative Dermatology

Année:

2001

Langue:

english

Fichier:

PDF, 256 KB

english, 2001

24

Pharmacological properties of the ornithine decarboxylase inhibitor 3-aminooxy-1-propanamine and several structural analogues

Helmut Mett, Jaroslav Stanek, Juan A. Lopez-Ballester, Juhani Jänne, Leena Alhonen, Riita Sinervirta, Jörg Frei, Urs Regenass

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 932 KB

english, 1993

25

Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern

Sami Heikkinen, Suvikki Suppola, Mari Malkki, Samir S. Deeb, Juhani Jänne, Markku Laakso

Journal:

Mammalian Genome

Année:

2000

Langue:

english

Fichier:

PDF, 543 KB

english, 2000

26

p53-Independent apoptosis in UV-irradiated mouse skin: possible inhibition by 50

Timo Kumlin, Päivi Heikkinen, Veli-Matti Kosma, Leena Alhonen, Juhani Jänne, Jukka Juutilainen

Journal:

Radiation and Environmental Biophysics

Année:

2002

Langue:

english

Fichier:

PDF, 58 KB

english, 2002

27

Downregulation of PPARs and SREBP by acyl-CoA-binding protein overexpression in transgenic rats

Sanna Oikari, Tiia Ahtialansaari, Miika V. Heinonen, Timo Mauriala, Seppo Auriola, Karlheinz Kiehne, Ulrich R. Fölsch, Juhani Jänne, Leena Alhonen, Karl-Heinz Herzig

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 398 KB

english, 2008

28

Proteomic analysis of livers from a transgenic mouse line with activated polyamine catabolism

Marc Cerrada-Gimenez, Jukka Häyrinen, Sisko Juutinen, Tuula Reponen, Juhani Jänne, Leena Alhonen

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 414 KB

english, 2010

29

Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis

Eija Pirinen, Helena Gylling, Paula Itkonen, Nagendra Yaluri, Sami Heikkinen, Marko Pietilä, Teemu Kuulasmaa, Maija Tusa, Marc Cerrada-Gimenez, Jussi Pihlajamäki, Leena Alhonen, Juhani Jänne, Tatu A.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 456 KB

english, 2010

30

Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice

Tekele M. Fashe, Tuomo A. Keinänen, Nikolay A. Grigorenko, Alex R. Khomutov, Juhani Jänne, Leena Alhonen, Marko Pietilä

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2010

31

Micrometeorological Observations of a Microburst in Southern Finland

Leena Järvi, Ari-Juhani Punkka, David M. Schultz, Tuukka Petäjä, Harri Hohti, Janne Rinne, Toivo Pohja, Markku Kulmala, Pertti Hari, Timo Vesala

Journal:

Boundary-Layer Meteorology

Année:

2007

Langue:

english

Fichier:

PDF, 965 KB

english, 2007

32

Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults

Marc Cerrada-Gimenez, Marko Pietilä, Suvikki Loimas, Eija Pirinen, Mervi T. Hyvönen, Tuomo A. Keinänen, Juhani Jänne, Leena Alhonen

Journal:

Transgenic Research

Année:

2011

Langue:

english

Fichier:

PDF, 383 KB

english, 2011

33

Fluorescent nanoparticles as labels for immunometric assay of C-reactive protein using two-photon excitation assay technology

Janne O Koskinen, Jonne Vaarno, Niko J Meltola, Juhani T Soini, Pekka E Hänninen, Juhani Luotola, Matti E Waris, Aleksi E Soini

Journal:

Analytical Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 499 KB

english, 2004

34

Quantitative determination of underivatized polyamines by using isotope dilution RP-LC–ESI-MS/MS

Merja R. Häkkinen, Tuomo A. Keinänen, Jouko Vepsäläinen, Alex R. Khomutov, Leena Alhonen, Juhani Jänne, Seppo Auriola

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2008

Langue:

english

Fichier:

PDF, 232 KB

english, 2008

35

Effect of Epidermal Polyamine Depletion on the Accumulation of Methylglyoxal Bis(guanylhydrazone) in Mouse Skin.

Kapyaho, Kirsti, Linnamaa, Kirsti, Janne, Juhani

Journal:

The Journal of Investigative Dermatology

Année:

1982

Fichier:

PDF, 2.15 MB

1982

36

Inhibition of DNA and Protein Synthesis in UV-Irradiated Mouse Skin by 2-Difluoromethylornithine, Methylglyoxal bis(Guanylhydrazone), and Their Combination.

Kapyaho, Kirsti, Lauharanta, Jorma, Janne, Juhani

Journal:

The Journal of Investigative Dermatology

Année:

1983

Fichier:

PDF, 2.92 MB

1983

37

Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures as a Result of Spermidine/Spermine N1-Acetyltransferase Overexpression

Pietila, Marko, Pirinen, Eija, Keskitalo, Salla, Juutinen, Sisko, Pasonen-Seppanen, Sanna, Keinanen, Tuomo, Alhonen, Leena, Janne, Juhani

Journal:

The Journal of Investigative Dermatology

Année:

2005

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2005

38

Genetic approaches to the cellular functions of polyamines in mammals

Juhani Jänne, Leena Alhonen, Marko Pietilä, Tuomo A. Keinänen

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 357 KB

english, 2004

39

Cerebral Energy Metabolism and Immediate Early Gene Induction Following Severe Incomplete Ischaemia in Transgenic Mice Overexpressing the Human Ornithine Decarboxylase Gene: Evidence that Putrescine is not Neurotoxic In Vivo

Jouko Lukkarainen, Risto A. Kauppinen, Jari Koistinaho, Maria Halmekytö, Leena Alhonen, Juhani Jänne

Journal:

European Journal of Neuroscience

Année:

1995

Langue:

english

Fichier:

PDF, 1.64 MB

english, 1995

40

Generation of Transgenic Dairy Cattle from Transgene-Analyzed and Sexed Embryos Produced In Vitro

Hyttinen, Juha-Matti, Peura, Teija, Tolvanen, Minna, Aalto, Jussi, Alhonen, Leena, Sinervirta, Riitta, Halmekytö, Maria, Myöhänen, Sanna, Jänne, Juhani

Journal:

Année:

1994

Fichier:

PDF, 427 KB

1994

41

Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: Effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

Sandmair, Anu-Maaria, Turunen, Marita, Tyynelä, Kristiina, Loimas, Sami, Vainio, Pauli, Vanninen, Ritva, Vapalahti, Matti, Bjerkvig, Rolf, Jänne, Juhani, Ylä-Herttuala, Seppo

Journal:

Cancer Gene Therapy

Année:

2000

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2000

42

Human prostate carcinoma cells as targets for herpes simplex virus thymidine kinase–mediated suicide gene therapy

Loimas, Sami, Toppinen, Marjo-Riitta, Visakorpi, Tapio, Jänne, Juhani, Wahlfors, Jarmo

Journal:

Cancer Gene Therapy

Année:

2001

Langue:

english

Fichier:

PDF, 600 KB

english, 2001

43

Bovine αs1-casein gene sequences direct high level expression of human granulocyte-macrophage colony-stimulating factor in the milk of transgenic mice

Mikko Uusi- Oukari, Juha-Matti Hyttinen, Veli-Pekka Korhonen, Anu Vasti, Leena Alhonen, Olli A. Janne, Juhani Janne

Journal:

Transgenic Research

Année:

1997

Langue:

english

Fichier:

PDF, 1.21 MB

english, 1997

44

Synthesis of (R)- and (S)-isomers of 1-methylspermidine

Nikolay A. Grigorenko, Jouko Vepsalainen, Aki Jarvinen, Tuomo Keinanen, Leena Alhonen, Juhani Janne, Alex R. Khomutov

Journal:

Mendeleev Communications

Année:

2005

Langue:

english

Fichier:

PDF, 91 KB

english, 2005

45

Simplifying the Estimation of Jugular Venous Pressure

Juha Sinisalo, Janne Rapola, Juhani Rossinen, Markku Kupari

Journal:

The American Journal of Cardiology

Année:

2007

Langue:

english

Fichier:

PDF, 85 KB

english, 2007

46

Analysis of the human hexokinase II promoter in vivo: lack of insulin response within 4.0 kb

Eija Pirinen, Sami Heikkinen, Mari Malkki, Samir S. Deeb, Juhani Jänne, Markku Laakso

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

2004

Langue:

english

Fichier:

PDF, 308 KB

english, 2004

47

Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment

Selma K Kaasinen, Mari Oksman, Leena Alhonen, Heikki Tanila, Juhani Jänne

Journal:

Pharmacology Biochemistry and Behavior

Année:

2004

Langue:

english

Fichier:

PDF, 572 KB

english, 2004

48

Enhanced ornithine decarboxylase activity is associated with attenuated rate of damage evolution and reduction of infarct volume in transient middle cerebral artery occlusion in the rat

Jouko A. Lukkarinen, Olli H.J. Gröhn, Leena I. Alhonen, Juhani Jänne, Risto A. Kauppinen

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 73 KB

english, 1999

49

Surface antigen expression and correlation with variable heavy-chain gene mutation status in chronic lymphocytic leukemia

Juhani Vilpo, Gerard Tobin, Janne Hulkkonen, Mikko Hurme, Ulf Thunberg, Christer Sundström, Leena Vilpo, Richard Rosenquist

Journal:

European Journal of Haematology

Année:

2003

Langue:

english

Fichier:

PDF, 210 KB

english, 2003

50

Animal disease models generated by genetic engineering of polyamine metabolism

Juhani Jänne, Leena Alhonen, Tuomo A. Keinänen, Marko Pietilä, Anne Uimari, Eija Pirinen, Mervi T. Hyvönen, Aki Järvinen

Journal:

Journal of Cellular and Molecular Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 534 KB

english, 2005